Projekt TEAM 5/2017 FNP

The project  entitled “Discovery and Characterization of non-canonical PIM kinase functions in lymphomas”, carried out within the TEAM programme of the Foundation for Polish Science is now starting.

Using chemical genomics and epigenomics, we plan to explore in detail chromatin-associated PIM functions in the most common lymphoid malignancy in adults, diffuse large B-cell lymphoma (DLBCL). We will study role of PIM kinases in epigenetic regulation of transcription in this disease end their role in enhancer function.  In addition, we plan to define the consequences of frequent PIM1 mutations, by performing functional and phosphoproteomic studies in cells expressing mutant PIM1.  

Institute of Hematology and Transfusion Medicine is one of the leading research institutions in Poland and a reference hematooncology center. Studies will be performed in a young, dynamic group, providing opportunities for successful publishing of research results. We offer scientific development oportunities, collaboration  with leading research institutions nationally and internationally and access to cutting-edge research technologies.

The project partners include:

  • University of Göttingen, Göttingen, Germany
  • International Institute of Molecular and Cellular Biology, Warsaw, Poland
  • Institute of Oncology and Maria Sklodowska-Curie Memorial Cancer Center, Warsaw, Poland
  • The Protein Crystallography Research Group, Malopolska Centre of
  • Biotechnology, Jagiellonian University, Kraków, Poland.

 

Project is supervised by prof. Przemysław Juszczynski, MD, PhD.

We open recruitment process for two open PhD candidate positions and for one postdoc position (full time job). Job offers and descriptions are available here: 

https://www.fnp.org.pl/assets/Oferta-pracy_TEAM_P-Juszczy%C5%84ski.pdf

https://www.fnp.org.pl/assets/Oferta-pracy-2_TEAM_P-Juszczy%C5%84ski.pdf